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Medchemexpress LLC Riliprubart 1mg | 1mg
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Riliprubart (SAR 445088) is an anti-C1s humanized IgG4 monoclonal antibody that inhibits activated C1s in the proximal portion of the classical complement system Riliprubart selectively inhibits activated C1s and prevents the enzymatic action of C1 on its substrates C4 and C2 thus inhibiting the formation of the classical pathway C3 convertase C4b2a Riliprubart can be used to study complement-mediated diseases such as systemic lupus erythematosus Recommend Isotype Controls Human IgG4 (S228P) kappa Isotype Control (HY-P99003)[1]
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Medchemexpress LLC Bezuclastinib | 1616385-51-3 | 98.8% | C19H17N5O | 1 MG
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Bezuclastinib (CGT9486) is an orally active, highly selective tyrosine kinase inhibitor that demonstrates potent activity against KIT D816V. It is used in the research of nonadvanced systemic mastocytosis (NonAdvSM).
- Orally active and highly selective tyrosine kinase inhibitor
- Potent activity against KIT D816V
- Used in research of nonadvanced systemic mastocytosis (NonAdvSM)
- Appears as a white to off-white solid
- Shows high selectivity to KIT D816V
- Minimal brain penetrance
- IC50 of <1 μM against c-Kit and c-kit D816V
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Medchemexpress LLC Activin RIB/ALK-4 R 100ug | 100ug
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Activin RIB also known as activin receptor type-1B (ACVR1B) or ALK-4 is a type I transmembrane serine/threonine kinase receptor that is part of the TGF- receptor superfamily Activin binds to a type II activin receptor (ACVR2or ACVR2B) and then recruits ACVR1B[1][2][3] Activin RIB/ALK-4 Protein Rhesus Macaque (HEK293 Fc) is produced in HEK293 cells with a C-Terminal Fc-tag It consists of 100 amino acids (R27-E126)
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Medchemexpress LLC 2-oxoindoline-6-carboxylic acid | 334952-09-9 | MFCD01415801 | 5g
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Indobufen impurity 4 is an impurity of Indobufen (HY-18763)
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Medchemexpress LLC Endoproteinase Lys-C | 72561-05-8 | 5 MG
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Endoproteinase Lys-C is a protease that cleaves proteins on the C-terminal side of lysine residues and is commonly used for protein sequencing. It is a key tool in biochemical research for understanding protein structure and function.
- Cleaves proteins at lysine residues
- Essential for protein sequencing applications
- Supports in-depth protein structure analysis
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Medchemexpress LLC HAP-1 | 329004-38-8 | 99.1% | 1335.47 | 25 MG
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HAP-1 is a synovial-targeted transduction peptide designed to facilitate the specific internalization of protein complexes into human and rabbit synovial cells. It can be fused to antimicrobial peptides, such as (KLAK)2, to generate proapoptotic peptides. This product is for research use only.
- Synovial-targeted transduction peptide
- Facilitates specific internalization of protein complexes into human and rabbit synovial cells
- Can be fused to antimicrobial peptides to generate proapoptotic peptides
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Medchemexpress LLC Pde7-in-3 | 908570-13-8 | 99.9% | 364.82 g/mol | C18H21ClN2O4 | 25 MG
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PDE7-IN-3 is a selective phosphodiesterase 7 (PDE7) inhibitor with reported analgesic activity. It is supplied as a white to off-white solid and is used in vitro and in vivo research to study inflammatory, neuropathic, visceral, and nociceptive pain pathways.
- Selective PDE7 inhibition for pharmacological studies.
- High purity (99.94%) suitable for research applications.
- Available in multiple small-scale quantities and DMSO solutions.
- Identified by CAS number 908570-13-8 for unambiguous referencing.
- Provided with datasheet, certificate of analysis, and safety data sheet.
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![Medchemexpress LLC 4-[[4-(2-methoxyethoxy)cyclohexyl]amino]-1-methyl-6-(1,3-thiazol-5-yl)quinolin-2-one | 1700637-55-3 | MFCD32062812 | 99.3% | 413.53 | C22H27N3O3S | 500MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000238383.png-250.jpg)
Medchemexpress LLC 4-[[4-(2-methoxyethoxy)cyclohexyl]amino]-1-methyl-6-(1,3-thiazol-5-yl)quinolin-2-one | 1700637-55-3 | MFCD32062812 | 99.3% | 413.53 | C22H27N3O3S | 500MG
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CD38 inhibitor 1 (compound 78c) is a potent small-molecule inhibitor of the CD38 enzyme intended for research use. It shows low-nanomolar inhibitory activity against human and mouse CD38 and is supplied as a high-purity solid for biochemical and cellular studies.
- Potent inhibition of CD38 with low-nanomolar IC50 values.
- Active against both human and mouse CD38.
- High purity suitable for research applications (reported ≥98%).
- Available in multiple package sizes, including a 500 mg option.
- Useful for studies of NAD+ metabolism and CD38-related pathways.
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Apexbio Technology LLC 2'-F-dUTP(Synonyms: 2'-Fluoro-2'-deoxyuridine-5'-triphosphate, 2'-Fluoro-dUTP, 2'-F-dUTP triphosphate), 5x100ul (100 mM).
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2 -F-dUTP is a bioactive nucleotide analog designed for research applications involving cellular signaling and enzyme activity pathways Its mechanism of action involves selective modulation of specific metabolic pathways potentially through competitive incorporation into nucleic acids or interference with enzyme functions In vitro studies with cultured cell lines suggest 2 -F-dUTP can alter cellular metabolism making it a valuable reagent for exploring disease pathways and facilitating therapeutic target identification in biomedical research
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Medchemexpress LLC 4-(1-Aminocyclopropyl)benzonitrile hydrochloride | 1369512-65-1 | C10H11ClN2 | 500 MG
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4-(1-Aminocyclopropyl)benzonitrile hydrochloride is a chemical compound commonly used as a laboratory chemical and in the manufacturing of various substances. This product appears as a solid and is stable under recommended storage conditions, making it suitable for a range of applications.
- Solid appearance
- Stable under recommended storage conditions
- Used as a laboratory chemical
- Used in the manufacture of substances
- Recommended powder storage: -20°C for 3 years or 4°C for 2 years
- Recommended in-solvent storage: -80°C for 6 months or -20°C for 1 month
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Medchemexpress LLC Epirubicin hydrochloride | 56390-09-1 | MFCD00941448 | 99.6% | 50 MG
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Epirubicin hydrochloride is a semisynthetic L-arabino derivative of doxorubicin. It acts as an antineoplastic agent by inhibiting Topoisomerase and DNA/RNA synthesis. It also functions as a Foxp3 inhibitor, inhibiting regulatory T cell activity.
- Exerts antitumor effects by complexing with DNA, causing damage and interfering with DNA, RNA, and protein synthesis.
- May also impact the integrity and activity of cellular membranes.
- Maximal cell kill occurs during the S phase of the cell cycle; higher concentrations affect early G2, G1, and M phases.
- Demonstrates antineoplastic activity against most cancer cells, with cytotoxicity to Hepatoma G2 cells (IC50 of 1.6 μg/mL at 24 hours).
- Clinically active against a broad range of tumor types including breast cancer, malignant lymphomas, soft tissue sarcomas, and lung cancer.
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![Medchemexpress LLC 2-hydroxy-3-[(1R)-1-(4-isopropyl-2-furyl)propylamino-cyclobutenylamino]-N,N-dimethylbenzamide | 473728-58-4 | 99.9% | 425.48 g·mol-1 | C23H27N3O5 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000215192.png-250.jpg)
Medchemexpress LLC 2-hydroxy-3-[(1R)-1-(4-isopropyl-2-furyl)propylamino-cyclobutenylamino]-N,N-dimethylbenzamide | 473728-58-4 | 99.9% | 425.48 g·mol-1 | C23H27N3O5 | 100 MG
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SCH 563705 is a potent, orally active small-molecule antagonist of the CXC chemokine receptors CXCR2 and CXCR1 used as a research compound to probe receptor signaling in inflammation and oncology. It demonstrates low-nanomolar receptor potency and is supplied as a high-purity solid suitable for in vitro and preclinical in vivo studies.
- Dual CXCR1/CXCR2 antagonism providing broad chemokine receptor coverage.
- Low-nanomolar potency (CXCR2 IC50 = 1.3 nM; CXCR1 IC50 = 7.3 nM).
- High chemical purity for reliable experimental results.
- Solid form suitable for formulation and dosing in preclinical studies.
- Characterized by CAS number and molecular weight for accurate identification.
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Medchemexpress LLC 1h-Isoindole-1,3(2h)-dione, 5,6-bis[(4-fluorophenyl)amino]- | 145915-60-2 | 98.9% | 365.33 | 50 MG
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CGP-53353 (DAPH-7) is a potent PKC inhibitor with IC50s of 0.41 μM and 3.8 μM for PKCβII and PKCβI, respectively. It inhibits glucose-induced cell proliferation and DNA synthesis in AoSMC and A10 cells and can be used for researching atherosclerosis in diabetic patients.
- Potent PKC inhibitor
- Inhibits glucose-induced cell proliferation and DNA synthesis in AoSMC and A10 cells
- Can be used for researching atherosclerosis of diabetic patients
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Apexbio Technology LLC LM 22A4 37988-18-4 50mg
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LM 22A4 (CAS 37988-18-4) is a small-molecule agonist that selectively targets the tropomyosin receptor kinase B (TrkB) a receptor implicated in neurotrophic signaling By activating TrkB-mediated pathways LM 22A4 modulates neuronal survival differentiation and synaptic plasticity This compound is extensively utilized in studies exploring neurobiological processes including neuronal maintenance and regeneration Its ability to influence TrkB signaling makes LM 22A4 a valuable tool in experimental models investigating mechanisms of neurodegeneration and neural repair
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000746445 ALCUDACIGIB TFA 10MG
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